北京爱情故事贴吧:医学或生物学翻译。

The hypothesis put forward by the CIGB, is that individuals could be specifically immunized against VEGF and VEGF receptor in a way that antibodies and specific cytotoxic T-cells (CTL) could be produced. These would be effective in: (a) neutralizing the biological activity of the VEGF overproduced by tumor cells, (b) directly killing tumor cells and the VEGF producing stromal cells by antibody and cell-mediated mechanisms, and (c) blocking VEGF receptors and promoting killing among activated tumor-associated endothelial cells.
With respect to the use of Avastin-like antibody-mediated passive immunotherapy, the active immunization approach could reduce the cost of treatment, make easier the combination of different target molecules in one single preparation, and avoid the need for continuous infusion of antibodies. Combination of active and passive immunotherapy could also provide advantages for patients that develop undesirable side effects, resistance, or tolerance.